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Disease Cycles

The cycles of diseases have had a profound impact on human history--from the plague to leprosy to today's continued struggles with malaria and sleeping sickness and AIDS.

Sample some of the following activities to learn more about disease cycles.


Places To Go | People To See | Things To Do | Teacher Resources | Bibliography

Places To Go

The following are places to go (some real and some virtual) to find out about disease cycles.

Center for Disease Control
Visit the Center for Disease Control. Read the Morbidity and Mortality Weekly Report from the Center for Disease Control to find out the most current information about the cycles of disease. Look at their Morbidity Tables to find out which states have Lungsthe highest numbers of infectious diseases. Utah has a high rate of E.coli infection. Some states have surprisingly high rates of rabies cases. Find out the number of people who got measles, mumps, rubella, or whooping cough in Utah (diseases that are preventable with vaccination!). Check out the CDC's list of diseases and find out the natural history of each disease, how it is spread, how it is diagnosed, its distribution, its prevention and control, and more.

American Lung Association
Visit the American Lung Associations and check out their lung diseases A-Z.

The Irish Potato Famine
Travel to Ireland to understand how the cycle of a plant disease named Phytophthora infestans affected that country in the 1840s. Discover how dependent this country was on potatoes for its main food crop and how the potato blight spread throughout the land. Over the course of the famine almost one million people died from starvation, and another one million left Ireland and immigrated mostly to America or to Canada .

Views of the Famine
Primary sources are original records created at the time historical events occurred. Read newspaper articles from the 1840s for historical perspective on the potato famine.

The Peloponnesian War
Visit ancient Greece in 430 B.C. and learn how disease affected the outcome of the Peloponnesian War. Pericles, one of the military leaders from Athens , had over 200,000 people flee from the outlying countryside and gather in Athens for protection from the pesky Spartans. While Athens was coping with this huge influx of people, the plague broke out and killed more than a third of the population of all of Athens , including Pericles. The effects of the plague and the war basically ended the Golden Age of Athens.

The Peopling of Mexico from Origins to Revolution
Take a trip to Mexico in the 1500s during the time of the Spanish invasion. The Europeans introduced diseases into Mexico and Central and South America that had a devastating impact on the native peoples. According to this site, after the Spanish invasion, the population of Mexico decreased by 33% in 10 years and by 95% in 75 years.

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People To See

Doctors Without Borders
Talk to the health care workers at Doctors Without Borders. These doctors form part of a medical relief agency that helps victims of armed conflict, epidemics, natural and man-made disasters, and others who lack health care due to geographic remoteness or ethnic marginalization. Annually, more than 2,000 volunteers representing 45 nationalities work in over 80 countries in front-line hospitals, refugee camps, disaster sites, towns, and villages.

BacteriaAmerican Museum of Natural History
Meet the Bacteria in the Cafeteria at the American Museum of Natural History's Infection Detection Protection site.

The Bad Bug Book
Talk to a "Bad Bug" and learn about the cycle of food-born illnesses.

National Inventors Hall of Fame
Meet Elizabeth Lee Hazen and Rachel Fuller Brown. They were pioneers in creating antibiotics in the 1950s.

DoctorAsk the Doctor Services
Choose from this long list of online medical advisors to find out more about the spread of infectious diseases.

The Official Mad Cow Disease Page
U.S. Food and Drug Administration
Meet some sick cows and learn about the cycle of this disease, how it is spread, who is at risk, how to keep yourself safe, and the impact that Bovine Spongiform Encephalopathy is having on the economy of affected countries

Sir Edwin Chadwick
Meet Sir Edwin Chadwick. He was a 19 th century sanitary reformer. As a journalist in London , he wrote about the appalling living conditions of the working class and the effect that these conditions seemed to have on their health. He was instrumental in helping to get a law passed called the UK Sanitary Act of 1866 that helped improve water systems, waste disposal, and housing standards. As a social reformer, he helped improve living conditions and disease cycles through sanitary science.

Answers.Com – Louis Pasteur
Re-acquaint yourself with Louis Pasteur. The reason he was able to figure our pasteurized milk was because he was an expert on germs and microorganisms. He discovered that heating milk to high temperatures killed germs and thus made milk safer and more accessible for longer periods of time to the general public. He also figured out that certain diseases could be prevented through injecting people with a weakened form of the disease in order to build immunity. So he was a pioneer in vaccination as well as germ-free milk.

BBC: John Snow
Get introduced to John Snow. In the 1850s, he discovered that the disease cycle of cholera was spread through water rather than through airborne sources.

Nova: The Most Dangerous Woman in America
Try to avoid Typhoid Mary. She was a carrier of the deadly disease of typhoid but was never sick herself. Her real name was Mary Mallon, and she was considered such a threat to public health in New York City in the early 1900s that she was quarantined on North Brother Island in the East River for 23 years.

Ignaz Semmelweis
Make the acquaintance of Ignaz Semmelweis. In 1861, he observed that the patients of doctors who performed autopsies suffered from more infections than the patients of doctors who did not perform autopsies. From this, he concluded that infection was spread by the contaminated hands of doctors. He recommended that doctors always thoroughly wash their hands before examining patients. His report was mostly discounted. Discouraged, he had a mental breakdown, was admitted to a mental institution, and died in 1865.

Nobel Prize: Robert Koch
Meet Robert Koch. In 1905, he was awarded the Nobel Prize in Physiology and Medicine. He worked with the new science of bacteriology and discovered that specific bacteria or organisms cause specific diseases. He also developed methods of culturing bacteria for study and methods to sterilize instruments with steam.

Nobel Prize: Alexander Fleming
Encounter Alexander Fleming. Find out how he felt about the fungus Penicillium notatum.

Jonas Salk
Meet Jonas Salk and learn how he developed a vaccine for polio. Prior to 1955, polio was a crippling disease to millions worldwide. Salk’s vaccine has virtually eradicated the disease.

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Things To Do

Sick person in bedCenter for Disease Control - Influenza Prevention and Control
Everyone gets the flu. Learn more about it. The Spanish flu of 1918-1919 caused about 500,000 deaths in the United States and 20 million deaths worldwide. The Hong Kong flu of 1968-1969 caused about 34,000 deaths in the United States. Influenza viruses are divided into three types, designated A, B, and C. These viruses are constantly changing which means that people are susceptible to getting the flu throughout their lives.

Epidemic ! The World of Infectious Disease
The microbes that cause most infectious diseases fall into three main groups: bacteria, viruses and protists. Microbes are everywhere-in the air you breathe, the water you drink, and the food you eat. Over 99% of all microbes are not harmful to humans. However, humans are at an increased risk of exposure to disease-causing microbes when ecosystems are upset by natural phenomena such as floods and droughts, as well as human disturbances including deforestation, introduction of agriculture, and war. Find out more about the natural and unnatural cycles of disease.

PenicillinWhat the Heck Is Penicillin
Find out how penicillin and other antibiotics prevent the cell wall of a bacterial cell from forming and, thereby, help to inhibit the spread of contagious disease.

Plague Factsheet
Plague is not an eradicated disease. The United States averages about 13 cases per year. There are three forms of plague : Bubonic, Septicemic, and Pneumonic. Plague is transmitted by fleas from infected animals to humans, by direct contact with infected tissues or fluids, or by respiratory droplets from cats and humans with pneumonic plague. In the U.S., the animals most likely to become infected are rock squirrels, prairie dogs, and other burrowing rodents.

Infections diseasesWorld Health Organization
Check out the World Health Organization to learn about the cycles of malaria infection and other worldwide diseases.

Antibiotics
An antibiotic (the Greek word anti which means against and the Greek word bio which means life) is any substance produced by a microorganism which can kill or inhibit the growth of a different microorganism. Find out how antibiotics can help stop the cycle of disease.

bacteriaBugs in the News
What is E.coli? What is mad cow disease? What is a virus? What is an antibody? Find out from this germy site.

New York State Department of Health Communicable Disease Fact Sheets
Find out how diphtheria, ringworm, typhoid fever, leprosy, and hantavirus are spread.

Insects, Disease, and Military History
Discover the relationship that diseases spread by insects have had on history. Entomologists (scientists who study insects) have long understood the impact that insects and disease have had on history.

MedHunters: Death on a Grand Scale
Plagues and infectious diseases are not ancient history. Learn about outbreaks in the 20 th century.

Tuberculosis
Learn about the disease that was called consumption for much of its history. Tuberculosis appears in Greek literature as far back as 450 B.C. During the 1800s in Europe , up to 25% of all deaths in Europe were thought to be caused by tuberculosis. Although modern medicine has found ways to treat this disease, it is still a huge health concern in developing nations.

Rocky Mountain Spotted Fever
Figure out how the cycles of the weather affect the cycles of ticks which then affects the spread of Rocky Mountain Spotted Fever.

World Health Organization: Smallpox
Discover how smallpox has affected humanity over the past 3000 years. This disease would sweep across continents and kill 30% of all who were infected with it. Between 65% and 80% of survivors of smallpox were marked with deep pox marks on their bodies and were often blinded by the disease. Learn how this disease has been eradicated through an aggressive campaign of immunization.

Division of Global Migration and Quarantine
Learn which diseases are quarantine-able in today’s world. Historically, there were three types of quarantine used as early methods of fighting infection: isolating sick individuals, restricting freedom of movement during epidemics, and isolating healthy people who had been exposed to infectious disease.

1918 Spanish Flu Pandemic
Influenza 1918
Learn about what has been called the most devastating outbreak of disease in the history of the world. The influenza pandemic in 1918 and 1919 killed between 20 and 40 million people. This particular strain of influenza, also known as Spanish flu, in one year killed more than the bubonic plague or Black Death killed in all its years. What are the chances of a new influenza strain affecting worldwide populations? What animals are the carriers of influenza virus? How is the virus transmitted from animals to humans?

WordReference.com
Learn a new word today. Asepsis is the process of inhibiting the growth and multiplication of microorganisms. It means wash your hands a lot.

Utah Department of Health Immunization Department
Learn which immunizations you need to protect against infectious diseases.

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Teacher Resources

Lesson Plan/Webquests/

Activities

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Bibliography

  • Corzine, Phyllis. The Black Death. San Diego, CA : Lucent Books, c1997.
  • Dehesh, Hadayat. How Not To Catch A Cold. Southfield, MI : Global Pub., 1996.
  • Demuth, Patricia. Achoo! : All About Colds. New York : Grosset & Dunlap, c1997.
  • Maynard, Christopher. Micro Monsters : Life Under the Microscope. New York : DK Pub., 1999.
  • McGowen, Tom. The Black Death. New York : F. Watts, c1995.
  • Silverstein, Alvin. Common Cold and Flu. Hillside, N.J., U.S.A. : Enslow Publishers, c1994.
  • Weitzman, Elizabeth. Let's Talk About Having the Flu. New York : Rosen Pub. Group's PowerKids Press, 1997.
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